(R, R) -CXCR2-IN-2
Product Specifications
CAS Number
1838123-22-0
Target
Others, CXCR
Related Pathways
Immunology/Inflammation, GPCR/G Protein, Others, Autophagy
Bioactivity
(R, R) -CXCR2-IN-2, a diastereoisomer of CXCR2-IN-2 (compound 68), is a brain-penetrant CXCR2 antagonist with a pIC50 of 9 in the Tango assay and 6.8 in the HWB Gro-α induced CD11b expression assay[1].
Smiles
CC1=CCC[C@H]1NC(=O)Nc1ccc(Cl)c(c1O)S(=O)(=O)[C@]1(C)CCOC1
Molecular Formula
C18H23ClN2O5S
Molecular Weight
414.9
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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