Sydowinin B
Product Specifications
CAS Number
58450-00-3
Target
Others
Related Pathways
Others
Bioactivity
Sydowinin B is a xanthone polyketide that has been found inA. sydowiiand has immunosuppressant activity.1It inhibits LPS- or concanavalin A-induced proliferation of isolated mouse splenic lymphocytes (IC50s = 19.2 and 20.8 ?g/ml, respectively) .2Sydowinin B inhibits superoxide generation in, and elastase release from, isolated human neutrophils induced by cytochalasin B and N-Formyl-Met-Leu-Phe with IC50values of 21.2 and 12.62 ?M, respectively.3
Smiles
COC(=O)c1c(O)ccc2oc3cc(CO)cc(O)c3c(=O)c12
Molecular Formula
C16H12O7
Molecular Weight
316.26
Shipping Conditions
Cool pack
Storage Temperature
-20°C
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