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Osimertinib mesylate

Product Specifications

CAS Number

1421373-66-1

Target

EGFR

Related Pathways

Angiogenesis, Tyrosine Kinase/Adaptors, JAK/STAT signaling

Purity

>99.99%

Bioactivity

Osimertinib mesylate (AZD-9291 mesylate) is an EGFR third-generation inhibitor that inhibits the T790M resistance mutation produced by second-generation EGFR inhibitors with irreversible and oral activity. Osimertinib mesylate has antitumor activity for the treatment of EGFR-mutated non-small-cell lung cancer.

Smiles

CS(O)(=O)=O.COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1cn(C)c2ccccc12

Molecular Formula

C29H37N7O5S

Molecular Weight

595.71

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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