Z-AEVD-FMK
Product Specifications
CAS Number
1135688-47-9
Target
ADC Linker
Related Pathways
Antibody-drug Conjugate/ADC Related
Bioactivity
Z-AEVD-FMK (Z-Ala-Glu-Val-Asp-Fluoromethyl Ketone) is a degradable ADC linker and caspase-10 inhibitor, reducing TNF-α/butyrate-induced apoptosis, and inhibiting Gal-9-induced apoptosis.
Smiles
[C@H](C(N[C@H](C(N[C@@H](CC(OC)=O)C(CF)=O)=O)C(C)C)=O)(NC([C@@H](NC(OCC1=CC=CC=C1)=O)C)=O)CCC(OC)=O
Molecular Formula
C28H39FN4O10
Molecular Weight
610.63
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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