PR-104
Product Specifications
CAS Number
851627-62-8
Target
Others, DNA Alkylator/Crosslinker
Related Pathways
Others, DNA Damage/DNA Repair
Bioactivity
PR-104 is a highly specific hypoxia-activated agent that cross-links DNA, enabling its application in various tumor xenograft models. Functioning as a pre-prodrug of nitrogen mustard, PR-104 undergoes efficient conversion to the dinitrobenzamide mustards alcohol form, known as PR-104A[1].
Smiles
N(CCOS(C)(=O)=O)(CCBr)C1=C(C(NCCOP(=O)(O)O)=O)C=C(N(=O)=O)C=C1N(=O)=O
Molecular Formula
C14H20BrN4O12PS
Molecular Weight
579.27
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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