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BIO5192 hydrate

Product Specifications

Target

Others|||Integrin

Related Pathways

Cytoskeletal Signaling|||Others

Bioactivity

BIO5192 hydrate is a selective and potent integrin ?4?1 (VLA-4) inhibitor (Kd < 10 pM) . The compound selectively binds to ?4?1 (IC50 = 1.8 nM) over various other integrins and results in a 30-fold increase in mobilization of murine hematopoietic stem and progenitors (HSPCs) over basal levels[1][2].

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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