VH 032 amide-PEG1-acid
Product Specifications
CAS Number
2172820-07-2
Target
Others, E3 Ligase Ligand-Linker Conjugate, DNA Alkylator/Crosslinker
Related Pathways
PROTAC, Others, DNA Damage/DNA Repair
Bioactivity
Functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC research and development; incorporates an E3 ligase ligand plus a PEG1 linker with terminal carboxylic acid ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
Smiles
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCC(O)=O)C(C)(C)C)cc1 |@:34|
Molecular Formula
C28H38N4O7S
Molecular Weight
574.69
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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