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VH 032 amide-PEG1-acid

Product Specifications

CAS Number

2172820-07-2

Target

Others, E3 Ligase Ligand-Linker Conjugate, DNA Alkylator/Crosslinker

Related Pathways

PROTAC, Others, DNA Damage/DNA Repair

Bioactivity

Functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC research and development; incorporates an E3 ligase ligand plus a PEG1 linker with terminal carboxylic acid ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

Smiles

Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCC(O)=O)C(C)(C)C)cc1 |@:34|

Molecular Formula

C28H38N4O7S

Molecular Weight

574.69

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Frequently Asked Questions

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