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IQ-1S free acid

Product Specifications

CAS Number

23146-22-7

Target

JNK, NF-κB

Related Pathways

MAPK, NF-κB

Purity

0.9905

Bioactivity

IQ-1S free acid (IQ-1S) is an effective and specific c-Jun N-Terminal Kinase Inhibitor. IQ-1S inhibits murine delayed-type hypersensitivity. IQ-1S can reduce inflammation and cartilage loss associated with CIA and can serve as a small-molecule modulator for mechanistic studies of JNK function in rheumatoid arthritis. IQ-1S is highly specific for JNK and that its neutral form is the most abundant species at physiologic pH.

Smiles

ON=C1c2ccccc2-c2nc3ccccc3nc12

Molecular Formula

C15H9N3O

Molecular Weight

247.25

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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