IQ-1S free acid
Product Specifications
CAS Number
23146-22-7
Target
JNK, NF-κB
Related Pathways
MAPK, NF-κB
Purity
0.9905
Bioactivity
IQ-1S free acid (IQ-1S) is an effective and specific c-Jun N-Terminal Kinase Inhibitor. IQ-1S inhibits murine delayed-type hypersensitivity. IQ-1S can reduce inflammation and cartilage loss associated with CIA and can serve as a small-molecule modulator for mechanistic studies of JNK function in rheumatoid arthritis. IQ-1S is highly specific for JNK and that its neutral form is the most abundant species at physiologic pH.
Smiles
ON=C1c2ccccc2-c2nc3ccccc3nc12
Molecular Formula
C15H9N3O
Molecular Weight
247.25
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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