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6β-Prostaglandin I1

Product Specifications

CAS Number

62770-50-7

Target

Prostaglandin Receptor, Others

Related Pathways

Others, GPCR/G Protein, Immunology/Inflammation

Bioactivity

6β-PGI1 is a stable PGI2 analog resistant to hydrolysis in aqueous solutions. 6β-PGI1 has a much longer half-life than PGI2, but a greatly reduced molar potency for receptor mediated function. 6β-PGI1 has a Kact for adenylate cyclase in NCB-20 cells of 4.2 μM compared with 18 nM for PGI2. The potency for vasodilation and inhibition of platelet aggregation is about 1% of PGI2.

Smiles

[H][C@]12C[C@@H](O)[C@H](\C=C\[C@@H](O)CCCCC)[C@@]1([H])C[C@H](CCCCC(O)=O)O2

Molecular Formula

C20H34O5

Molecular Weight

354.487

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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