6β-Prostaglandin I1
Product Specifications
CAS Number
62770-50-7
Target
Prostaglandin Receptor, Others
Related Pathways
Others, GPCR/G Protein, Immunology/Inflammation
Bioactivity
6β-PGI1 is a stable PGI2 analog resistant to hydrolysis in aqueous solutions. 6β-PGI1 has a much longer half-life than PGI2, but a greatly reduced molar potency for receptor mediated function. 6β-PGI1 has a Kact for adenylate cyclase in NCB-20 cells of 4.2 μM compared with 18 nM for PGI2. The potency for vasodilation and inhibition of platelet aggregation is about 1% of PGI2.
Smiles
[H][C@]12C[C@@H](O)[C@H](\C=C\[C@@H](O)CCCCC)[C@@]1([H])C[C@H](CCCCC(O)=O)O2
Molecular Formula
C20H34O5
Molecular Weight
354.487
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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