5-cis Carbaprostacyclin
Product Specifications
CAS Number
69609-77-4
Target
Prostaglandin Receptor, Others, PPAR
Related Pathways
DNA Damage/DNA Repair, Others, GPCR/G Protein, Immunology/Inflammation, Metabolism
Bioactivity
5-cis Carbaprostacyclin, a stable analog of PGI2 and an isomer of carbaprostacyclin, is a weak inhibitor of human platelet aggregation with an IC50 of 2.8 μM compared to 0.3 μM for carbaprostacyclin. It is a much weaker effector of rabbit mesenteric artery relaxation with an EC50 of 104 μM compared to 5.9 μM for carbaprostacyclin and even antagonizes the adenylate cyclase activation induced by carbaprostacyclin.
Smiles
C(=C/[C@H](CCCCC)O)\[C@@H]1[C@@]2([C@@](C\C(=C\CCCC(O)=O)\C2)(C[C@H]1O)[H])[H]
Molecular Formula
C21H34O4
Molecular Weight
350.49
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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