Cobimetinib
Product Specifications
CAS Number
934660-93-2
Target
MEK, Apoptosis
Related Pathways
MAPK, Apoptosis
Purity
>99.99%
Bioactivity
Cobimetinib (GDC-0973) is a MEK1 inhibitor (IC50=4.2 nM) with selective and oral activity. Cobimetinib exhibits antitumor activity, inhibiting tumor cell proliferation and inducing apoptosis.
Smiles
C(=O)(C1=C(NC2=C(F)C=C(I)C=C2)C(F)=C(F)C=C1)N3C[C@](O)(C3)[C@@H]4CCCCN4
Molecular Formula
C21H21F3IN3O2
Molecular Weight
531.31
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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