Cobimetinib

Product Specifications

CAS Number

934660-93-2

Target

MEK|||Apoptosis

Related Pathways

MAPK|||Apoptosis

Purity

>99.99%

Bioactivity

Cobimetinib (GDC-0973) is a MEK1 inhibitor (IC50=4.2 nM) with selective and oral activity. Cobimetinib exhibits antitumor activity, inhibiting tumor cell proliferation and inducing apoptosis.

Smiles

C(=O)(C1=C(NC2=C(F)C=C(I)C=C2)C(F)=C(F)C=C1)N3C[C@](O)(C3)[C@@H]4CCCCN4

Molecular Formula

C21H21F3IN3O2

Molecular Weight

531.31

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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