Beauveriolide III
Product Specifications
CAS Number
221111-70-2
Target
Beta Amyloid
Related Pathways
Neuroscience
Purity
0.9948
Bioactivity
Beauveriolide III, a cyclodepsipeptide found in Beauveria fungi, inhibits lipid droplet formation (at 3-10 μM) and cholesterol synthesis (IC50=0.41 μM) . This compound also suppresses acyl-coenzyme A:cholesterol acyltransferase (ACAT) activity (IC50=5.5 μM) and reduces atherosclerotic lesion size in Ldlr-/- and ApoE-/- mouse models (25-50 mg/kg) .
Smiles
C([C@@H]1NC(=O)C[C@@]([C@H](CCCC)C)(OC(=O)[C@@]([C@H](CC)C)(NC(=O)[C@H](C)NC1=O)[H])[H])C2=CC=CC=C2
Molecular Formula
C27H41N3O5
Molecular Weight
487.63
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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