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Beauveriolide III

Product Specifications

CAS Number

221111-70-2

Target

Beta Amyloid

Related Pathways

Neuroscience

Purity

0.9948

Bioactivity

Beauveriolide III, a cyclodepsipeptide found in Beauveria fungi, inhibits lipid droplet formation (at 3-10 μM) and cholesterol synthesis (IC50=0.41 μM) . This compound also suppresses acyl-coenzyme A:cholesterol acyltransferase (ACAT) activity (IC50=5.5 μM) and reduces atherosclerotic lesion size in Ldlr-/- and ApoE-/- mouse models (25-50 mg/kg) .

Smiles

C([C@@H]1NC(=O)C[C@@]([C@H](CCCC)C)(OC(=O)[C@@]([C@H](CC)C)(NC(=O)[C@H](C)NC1=O)[H])[H])C2=CC=CC=C2

Molecular Formula

C27H41N3O5

Molecular Weight

487.63

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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