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Beauveriolide I

Product Specifications

CAS Number

154491-55-1

Target

Others|||Endogenous Metabolite

Related Pathways

Others|||Metabolism

Bioactivity

Beauveriolide I is a cyclodepsipeptide that has been found inBeauveriaand an inhibitor of lipid droplet formation.1It inhibits lipid droplet formation when used at concentrations of 3 and 10 ?M, as well as inhibits cholesterol synthesis (IC50= 0.78 ?M), in primary mouse peritoneal macrophages.1,2Beauveriolide I also inhibits acyl-coenzyme A:cholesterol acyltransferase (ACAT) activity in mouse macrophage membranes (IC50= 6 ?M) .2

Smiles

[H][C@]1(CC(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](C)C(=O)N[C@]([H])(CC(C)C)C(=O)O1)[C@@H](C)CCCC

Molecular Formula

C27H41N3O5

Molecular Weight

487.63

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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