17R (18S) -EpETE
Product Specifications
CAS Number
725246-18-4
Target
Calcium Channel, Others
Related Pathways
Membrane transporter/Ion channel, Metabolism, Others
Bioactivity
17R (18S) -EpETE is an oxylipin and a cytochrome P450 metabolite of eicosapentaenoic acid .1,217R (18S) -EpETE is an activator of large-conductance calcium-activated potassium (BKCa) channels, increasing the potassium current amplitude by 15-fold in isolated rat cerebral artery vascular smooth muscle cells (VSMCs) at +60 mV when used at a concentration of 50 nM.2It has negative chronotropic effects in isolated neonatal rat cardiomyocytes (NRCMs; EC50= ~1-2 nM) and prevents calcium-induced increases in the spontaneous beating of NRCMs.3,4
Smiles
CC[C@@H]1O[C@@H]1C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O
Molecular Formula
C20H30O3
Molecular Weight
318.457
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
GTR15127001 1 Vial
Lentiviral mouse Ctsa shRNA (UAS) - Lentiviral mouse Ctsa shRNA (UAS) (25)
Sign In for Pricing
View Details 
LS057604-20ug 20 µg
TRMT9B (NM_020844) Human Over-expression Lysate
Sign In for Pricing
View Details ED0548Hu-01 96 Well
Human Anti-Toxoplasma gondii IgG, Anti-Tg IgG ELISA KIT
Sign In for Pricing
View Details 168274 100 µg
IL-2 (Interleukin-2, IL-2, IL2, T-cell growth factor, TCGF, Aldesleukin, Lymphokine) (Biotin)
Sign In for Pricing
View Details