AZD 3147
Product Specifications
CAS Number
1101810-02-9
Target
MTOR
Related Pathways
PI3K/Akt/mTOR signaling
Purity
0.9999
Bioactivity
AZD 3147 is an inhibitor of mTORC with IC50s of 40.7 and 5.75 nM for mTORC1 and mTORC2. AZD 3147 shows IC50s of 912, 5495, 9333, and 6310 nM for PI3Kα, PI3Kβ, PI3Kδ, and PI3Kγ, respectively.
Smiles
S(=O)(=O)(C1(CC1)C=2C=C(N=C(N2)C3=CC=C(NC(NCCO)=S)C=C3)N4[C@@H](C)COCC4)C5CC5
Molecular Formula
C24H31N5O4S2
Molecular Weight
517.66
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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