Azelaoyl PAF
Product Specifications
CAS Number
354583-69-0
Target
PPAR, Integrin
Related Pathways
Cytoskeletal Signaling, Metabolism, DNA Damage/DNA Repair
Bioactivity
Azelaoyl PAF is a potent PPARγ agonist that competitively binds thiazolidinediones with potency comparable to rosiglitazone. In atherosclerosis studies, Azelaoyl PAF promotes the uptake of oxidized low-density lipoprotein (oxLDL) by macrophages by upregulating CD36 expression. In fibroblasts from Friedreich's ataxia (FRDA) patients, Azelaoyl PAF significantly increased mRNA and protein levels of ferritin.
Smiles
[C@@H](COP(OCC[N+](C)(C)C)(=O)[O-])(OC(CCCCCCCC(O)=O)=O)COCCCCCCCCCCCCCCCC
Molecular Formula
C33H66NO9P
Molecular Weight
651.85
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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