8-iso Prostaglandin F1β
Product Specifications
CAS Number
26771-95-9
Target
PPAR, ROCK, Rho, Prostaglandin Receptor, Tyrosinase
Related Pathways
DNA Damage/DNA Repair, Cytoskeletal Signaling, Stem Cells, GPCR/G Protein, Metabolism, Immunology/Inflammation, Cell Cycle/Checkpoint, Proteases/Proteasome
Bioactivity
8-iso Prostaglandin F1β, an isoprostane produced from arachidonic acid, induces concentration-dependent vasoconstrictor effects in pulmonary arteries (PA), pulmonary veins (PV) and mesenteric arteries (MA) through the activation ofTXA2R, tyrosine kinase and Rho kinase.
Smiles
C(CCCCCC(O)=O)[C@H]1[C@@H](/C=C/[C@H](CCCCC)O)[C@H](O)C[C@H]1O
Molecular Formula
C20H36O5
Molecular Weight
356.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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