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8-iso Prostaglandin F1?

Product Specifications

CAS Number

26771-95-9

Target

PPAR|||ROCK|||Rho|||Prostaglandin Receptor|||Tyrosinase

Related Pathways

DNA Damage/DNA Repair|||Cytoskeletal Signaling|||Stem Cells|||GPCR/G Protein|||Metabolism|||Immunology/Inflammation|||Cell Cycle/Checkpoint|||Proteases/Proteasome

Bioactivity

8-iso Prostaglandin F1?, an isoprostane produced from arachidonic acid, induces concentration-dependent vasoconstrictor effects in pulmonary arteries (PA), pulmonary veins (PV) and mesenteric arteries (MA) through the activation ofTXA2R, tyrosine kinase and Rho kinase.

Smiles

C(CCCCCC(O)=O)[C@H]1[C@@H](/C=C/[C@H](CCCCC)O)[C@H](O)C[C@H]1O

Molecular Formula

C20H36O5

Molecular Weight

356.5

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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