What is the catalog number for BMP-22?

The catalog number for BMP-22 is T36138.

What sizes are available for BMP-22?

BMP-22 is available in the following size(s): 1 mg, 5 mg, 10 mg, 25 mg.

How many pack sizes does BMP-22 come in?

BMP-22 is available in 4 different pack sizes.

BMP-22 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures BMP-22?

BMP-22 is manufactured by Molfinity.

What is the estimated delivery time for BMP-22?

Estimated delivery time for BMP-22 is approximately 10 business day(s), depending on your location.

BMP-22

Product Specifications

CAS Number

1306684-90-1

Target

Others, PDE

Related Pathways

Metabolism, Others

Bioactivity

BMP-22 is an inhibitor of autotaxin (IC50 = 170 nM) . It is selective for autotaxin over the phosphodiesterases NPP6 and NPP7 at 10 μM. BMP-22 (0.1-1,000 nM) inhibits autotaxin-mediated production of lysophosphatidic acid (LPA) from lysophosphatidylcholine in vitro in a concentration-dependent manner. It inhibits LPC-dependent MM1 cell invasion of a human umbilical vein endothelial cell (HUVEC) monolayer. BMP-22 (0.5 mg/kg per day) decreases the number of lung metastatic foci in a B16/F10 syngeneic mouse melanoma model of lung metastasis.