What is the catalog number for RMC-5552?

The catalog number for RMC-5552 is T36089.

What sizes are available for RMC-5552?

RMC-5552 is available in the following size(s): 1 mg, 5 mg, 10 mg, 1 mL - 10 mM (in DMSO), 25 mg.

How many pack sizes does RMC-5552 come in?

RMC-5552 is available in 5 different pack sizes.

Is RMC-5552 in stock?

RMC-5552 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures RMC-5552?

RMC-5552 is manufactured by Molfinity.

What is the estimated delivery time for RMC-5552?

Estimated delivery time for RMC-5552 is approximately 10 business day(s), depending on your location.

RMC-5552

Product Specifications

CAS Number

2382768-62-7

Target

MTOR

Related Pathways

PI3K/Akt/mTOR signaling

Bioactivity

RMC-5552 is a potent and selective inhibitor of mTORC1 that blocks phosphorylation of downstream signaling targets pS6K and p4EBP1 with IC50 values of 0.14 nM and 0.48 nM, respectively. RMC-5552 shows markedly reduced inhibition of pAKT (IC50 19 nM), achieving approximately 40-fold selectivity for mTORC1 over mTORC2. RMC-5552 has demonstrated anticancer activity, supporting its potential use as a therapeutic agent in oncology and as a research tool for dissecting mTOR signaling pathways.

Smiles

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