N-Oleoyl-L-Serine
Product Specifications
CAS Number
107743-37-3
Target
Apoptosis
Related Pathways
Apoptosis
Purity
0.9976
Bioactivity
N-Oleoyl-L-Serine (N-Oleoylserine) is an endogenous long-chain fatty acid amide that is a lipid modulator of bone remodeling and stimulates osteoclast apoptosis which can be used to study osteoporosis. N-Oleoyl-L-Serine showed high activity in an osteoblast proliferation assay.N-Oleoyl-L-Serine promotes osteoclast apoptosis by inhibiting Erk1/2 phosphorylation and expression of nuclear ?B ligand (RANKL) receptor activator in bone marrow stromal cells and osteoblasts, which attenuates osteoclast populations.
Smiles
N([C@H](C(O)=O)CO)C(CCCCCCC/C=C\CCCCCCCC)=O
Molecular Formula
C21H39NO4
Molecular Weight
369.54
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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