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Sodium dichloroacetate

Product Specifications

CAS Number

2156-56-1

Target

PDK, ROS, Reactive Oxygen Species, Apoptosis, Dehydrogenase, Na-K-Cl cotransporter

Related Pathways

Membrane transporter/Ion channel, Metabolism, PI3K/Akt/mTOR signaling, NF-κB, Apoptosis, Immunology/Inflammation

Purity

0.9987

Bioactivity

Sodium dichloroacetate (BCA), a specific inhibitor of pyruvate dehydrogenase kinase (PDK) with IC50 values of 183 and 80 μM for PDK2 and PDK4 respectively, has been shown to derepress a mitochondrial potassium-ion channel axis, trigger apoptosis in cancer cells, and inhibit tumor growth.

Smiles

C(C(=O)[O-])(Cl)Cl.[Na+]

Molecular Formula

C2HCl2NaO2

Molecular Weight

150.92

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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