Sodium dichloroacetate
Product Specifications
CAS Number
2156-56-1
Target
PDK|||ROS|||Reactive Oxygen Species|||Apoptosis|||Dehydrogenase|||Na-K-Cl cotransporter
Related Pathways
Membrane transporter/Ion channel|||Metabolism|||PI3K/Akt/mTOR signaling|||NF-?B|||Apoptosis|||Immunology/Inflammation
Purity
0.9987
Bioactivity
Sodium dichloroacetate (BCA), a specific inhibitor of pyruvate dehydrogenase kinase (PDK) with IC50 values of 183 and 80 ?M for PDK2 and PDK4 respectively, has been shown to derepress a mitochondrial potassium-ion channel axis, trigger apoptosis in cancer cells, and inhibit tumor growth.
Smiles
C(C(=O)[O-])(Cl)Cl.[Na+]
Molecular Formula
C2HCl2NaO2
Molecular Weight
150.92
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
TL515251V 500 µL Each
Smdt1 Mouse shRNA Lentiviral Particle (Locus ID 69029)
Sign In for Pricing
View Details