SY-5609
Product Specifications
CAS Number
2417302-07-7
Target
Apoptosis|||CDK
Related Pathways
Apoptosis|||Cell Cycle/Checkpoint
Purity
>99.99%
Bioactivity
SY-5609 (CDK7-IN-3) is a selective non-covalent CDK7 inhibitor (Kd value is 0.07 nM), with weak inhibitory activity against CDK2, CDK9 and CDK12 with IC50 values ??of 5.5, 1.9 and 1.7 ?M, respectively, and has anti-tumor activity and inhibits cell apoptosis.
Smiles
C(F)(F)(F)C=1C(C=2C=3C(NC2)=C(P(C)(C)=O)C(C#N)=CC3)=NC(N[C@H]4CCC(C)(C)NC4)=NC1
Molecular Formula
C23H26F3N6OP
Molecular Weight
490.46
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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