Flumequine-13C3

Flumequine-13C3is intended for use as an internal standard for the quantification of flumequine by GC- or LC-MS. Flumequine is a fluoroquinolone antibiotic.1It is active againstS. aureus, S. pyogenes, B. subtilis, E. coli, P. aeruginosa, S. faecalis, andK. pneumoniae (MICs = 1-100 μg/ml) . Flumequine is also active against field isolates of B. hyodysenteriae (MICs = 6.25-200 μg/ml) .2It inhibits DNA gyrase, disrupting supercoiling of bacterial DNA to block transcription and replication.3