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PF-05381941

Product Specifications

CAS Number

1474022-02-0

Target

MAPK, MAP3K, p38 MAPK

Related Pathways

MAPK

Purity

0.9804

Bioactivity

PF-05381941 is a selective and potent dual inhibitor of TAK1 and p38α with IC 50 =156 nM/186nM that inhibits the kinase activity of TAK1 by binding to its active site.

Smiles

N#CC1=CC=CC(=C1)N2N=C(C=C2NC(=O)NC3=CC=C(OC=4C=CN=CC4)C(=C3)C)C(C)(C)C

Molecular Formula

C27H26N6O2

Molecular Weight

466.53

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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