BFH772
Product Specifications
CAS Number
890128-81-1
Target
VEGFR
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis
Purity
0.9989
Bioactivity
BFH772, a structure analogue of BAW2881, is a potent and selective VEGF inhibitor. BFH772 is highly effective at targeting VEGFR2 kinase with an IC50 value of 3 nM. BFH772 inhibits the ligand induced autophosphorylation of RET, PDGFR, and KIT kinases, with IC50 values ranging between 30 and 160 nM.
Smiles
OCc1cc(Oc2ccc3c(cccc3c2)C(=O)Nc2cccc(c2)C(F)(F)F)ncn1
Molecular Formula
C23H16F3N3O3
Molecular Weight
439.39
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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