Benastatin A
Product Specifications
CAS Number
138968-85-1
Target
Others, GST
Related Pathways
Oxidation-Reduction, Others
Bioactivity
Benastatin A is a polyketide synthase-derived benastatin that has been found inStreptomycesand has diverse biological activities.1,2,3It inhibits glutathione S-transferase (GST; Ki= 5 μM for the rat liver enzyme) .2Benastatin A is active against several bacteria, including methicillin-resistantS. aureus (MRSA; MIC = 3.12 μg/ml) . It induces apoptosis and cell cycle arrest at the G1/G0phase in Colon 26 mouse colon cancer cells when used at concentrations of 20 and 16 μM, respectively.3
Smiles
CCCCCc1cc2ccc3c(O)c4C(=O)c5c(O)cc(O)cc5C(C)(C)c4cc3c2c(O)c1C(O)=O
Molecular Formula
C30H28O7
Molecular Weight
500.54
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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