Cutamesine dihydrochloride
Product Specifications
CAS Number
165377-44-6
Target
Sigma receptor
Related Pathways
GPCR/G Protein
Purity
0.9996
Bioactivity
Cutamesine dihydrochloride (SA4503 dihydrochloride) is a selective σ1 receptor agonist (IC50: 17.4 nM) . It shows selectivity for σ1 over σ2 receptors, and inhibits angiotensin II-induced cardiomyocyte hypertrophy in vitro and attenuates myocardial hypertrophy in vivo. In a rat model of experimental stroke, it enhances brain plasticity and sensorimotor function.
Smiles
Cl.Cl.COc1ccc(CCN2CCN(CCCc3ccccc3)CC2)cc1OC
Molecular Formula
C23H32N2O2·2HCl
Molecular Weight
441.43
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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