Simotinib
Product Specifications
CAS Number
944258-89-3
Target
EGFR
Related Pathways
JAK/STAT signaling, Angiogenesis, Tyrosine Kinase/Adaptors
Purity
0.997
Bioactivity
Simotinib (AL-6802) is a selective and orally bioactive EGFR tyrosine kinase inhibitor (IC50: 19.9 nM) with anti-tumour activity for the study of non-small cell lung cancer.
Smiles
COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCN1CC2(CC2)C2(C1)OCCO2
Molecular Formula
C25H26ClFN4O4
Molecular Weight
500.95
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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