Atiprimod dihydrochloride
Product Specifications
CAS Number
130065-61-1
Target
Apoptosis, Caspase, p62, Autophagy, STAT, ATG, JAK, Others, ROS
Related Pathways
Others, Angiogenesis, Apoptosis, Immunology/Inflammation, Tyrosine Kinase/Adaptors, JAK/STAT signaling, Proteases/Proteasome, Autophagy, Chromatin/Epigenetic, Stem Cells
Bioactivity
JAK2 inhibitor (IC50 = 397 nM) . Also inhibits STAT3 and STAT5 phosphorylation. Inhibits cell growth and induces apoptosis in cells expressing the JAK2V617F mutation.
Smiles
Cl.Cl.CCCC1(CCC)CCC2(CCN(CCCN(CC)CC)C2)CC1
Molecular Formula
C22H46Cl2N2
Molecular Weight
409.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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