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Atiprimod dihydrochloride

Product Specifications

CAS Number

130065-61-1

Target

Apoptosis, Caspase, p62, Autophagy, STAT, ATG, JAK, Others, ROS

Related Pathways

Others, Angiogenesis, Apoptosis, Immunology/Inflammation, Tyrosine Kinase/Adaptors, JAK/STAT signaling, Proteases/Proteasome, Autophagy, Chromatin/Epigenetic, Stem Cells

Bioactivity

JAK2 inhibitor (IC50 = 397 nM) . Also inhibits STAT3 and STAT5 phosphorylation. Inhibits cell growth and induces apoptosis in cells expressing the JAK2V617F mutation.

Smiles

Cl.Cl.CCCC1(CCC)CCC2(CCN(CCCN(CC)CC)C2)CC1

Molecular Formula

C22H46Cl2N2

Molecular Weight

409.52

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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