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RNF5 inhibitor inh-02

Product Specifications

CAS Number

324579-65-9

Target

ATG, E1/E2/E3 Enzyme

Related Pathways

Ubiquitination, Autophagy

Purity

0.9923

Bioactivity

RNF5 inhibitor inh-02 is a selective inhibitor of the ubiquitin ligase RNF5/RMA1, which can significantly rescue F508del-CFTR (cystic fibrosis transmembrane conductance regulator with a deletion at position 508 of phenylalanine) and regulate ATG4B and paxillin, making it useful for studying cystic fibrosis (CF) .

Smiles

N=1SC(=NC(=NC=2C=CC=CC2)C=3C=CC=CC3)N(C1C)CC=4C=CC=CC4

Molecular Formula

C23H20N4S

Molecular Weight

384.5

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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