RNF5 inhibitor inh-02
Product Specifications
CAS Number
324579-65-9
Target
ATG, E1/E2/E3 Enzyme
Related Pathways
Ubiquitination, Autophagy
Purity
0.9923
Bioactivity
RNF5 inhibitor inh-02 is a selective inhibitor of the ubiquitin ligase RNF5/RMA1, which can significantly rescue F508del-CFTR (cystic fibrosis transmembrane conductance regulator with a deletion at position 508 of phenylalanine) and regulate ATG4B and paxillin, making it useful for studying cystic fibrosis (CF) .
Smiles
N=1SC(=NC(=NC=2C=CC=CC2)C=3C=CC=CC3)N(C1C)CC=4C=CC=CC4
Molecular Formula
C23H20N4S
Molecular Weight
384.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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