Berotralstat
Product Specifications
CAS Number
1809010-50-1
Target
Serine Protease|||Others
Related Pathways
Others|||Proteases/Proteasome
Bioactivity
Berotralstat (BCX7353) is a second-generation, synthetic, and orally active plasma kallikrein inhibitor with low toxicity. It is highly specific and effectively used in the research of hereditary angioedema (HAE) attacks. Berotralstat functions by inhibiting the enzymatic activity of plasma kallikrein, which is responsible for the release of bradykinin. This blocking mechanism targets the major biologic peptide involved in the promotion of swelling and pain associated with HAE attacks[1][2].
Smiles
NCc1cccc(c1)-n1nc(cc1C(=O)Nc1cc(ccc1F)[C@H](NCC1CC1)c1cccc(c1)C#N)C(F)(F)F
Molecular Formula
C30H26F4N6O
Molecular Weight
562.56
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
