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19 (S) -HETE

Product Specifications

CAS Number

115461-40-0

Target

Prostaglandin Receptor|||Others

Related Pathways

Immunology/Inflammation|||GPCR/G Protein|||Others

Bioactivity

19-HETE is one of the major cytochrome P450 (CYP450) metabolites of arachidonic acid that is released from the kidney in response to angiotensin II. When formed by the CYP2E1 isoform, 19-HETE is composed of 70% and 30% of the (S) and (R) stereoisomers, respectively. Both 19 (S) - and 19 (R) -HETE are potent vasodilators of renal preglomerular vessels. 19 (S) -HETE stimulates both renal sodium-potassium ATPase and volume absorption in the rabbit proximal straight tubule.

Smiles

C[C@H](O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O

Molecular Formula

C20H32O3

Molecular Weight

320.473

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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