19 (S) -HETE
Product Specifications
CAS Number
115461-40-0
Target
Prostaglandin Receptor|||Others
Related Pathways
Immunology/Inflammation|||GPCR/G Protein|||Others
Bioactivity
19-HETE is one of the major cytochrome P450 (CYP450) metabolites of arachidonic acid that is released from the kidney in response to angiotensin II. When formed by the CYP2E1 isoform, 19-HETE is composed of 70% and 30% of the (S) and (R) stereoisomers, respectively. Both 19 (S) - and 19 (R) -HETE are potent vasodilators of renal preglomerular vessels. 19 (S) -HETE stimulates both renal sodium-potassium ATPase and volume absorption in the rabbit proximal straight tubule.
Smiles
C[C@H](O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O
Molecular Formula
C20H32O3
Molecular Weight
320.473
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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