Trichostatin C
Product Specifications
CAS Number
68676-88-0
Target
Apoptosis, Antifungal, Others, HDAC
Related Pathways
Apoptosis, Chromatin/Epigenetic, DNA Damage/DNA Repair, Microbiology/Virology, Others
Bioactivity
Trichostatin C is a glycosylated derivative of trichostatin A , the antifungal antibiotic that reversibly inhibits histone deacetylase. Trichostatin C is reported to be the first example of a glucopyranosyl hydroxamate identified in nature. It has been shown to induce the differentiation of a mouse erythroleukemia cell line and to increase histone H4 acetylation in B cells, though at higher concentrations than trichostatin A.
Smiles
C[C@H](\C=C(/C)\C=C\C(=O)NO[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)C(=O)c1ccc(cc1)N(C)C
Molecular Formula
C23H32N2O8
Molecular Weight
464.515
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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