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ML-345

Product Specifications

CAS Number

1632125-79-1

Target

MMP

Related Pathways

Proteases/Proteasome

Bioactivity

ML-345 is a selective and potent IDE (insulin-degrading enzyme) inhibitor (IC50=188 nM) targeting the cysteine residue Cys819 in IDE, suitable for studying type 2 diabetes and Alzheimer's disease.

Smiles

O=C1C2=CC(F)=CC=C2SN1C3=CC(=CC=C3N4CCOCC4)S(=O)(=O)N5CCOCC5

Molecular Formula

C21H22FN3O5S2

Molecular Weight

479.55

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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