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JMV3002

Product Specifications

CAS Number

925239-03-8

Target

GHSR, Others

Related Pathways

Others, GPCR/G Protein

Bioactivity

JMV3002 is a potent ghrelin receptor antagonist with an IC50 value of 1.1 nM in vitro. At 80 μg/kg, JMV3002 inhibits hexarelin-stimulated food intake by up to 98% in rats. It does not induce growth hormone release nor inhibit hexarelin-stimulated growth hormone secretion at a dose of 160 μg/kg in infant rats.

Smiles

C(N1C([C@@H](CC=2C=3C(NC2)=CC=CC3)NC(=O)C4=CC=CC=N4)=NN=C1CCC5=CC=CC=C5)C6=C(OC)C=C(OC)C=C6

Molecular Formula

C35H34N6O3

Molecular Weight

586.68

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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