PLX8394
Product Specifications
CAS Number
1393466-87-9
Target
Raf
Related Pathways
MAPK
Purity
>99.99%
Bioactivity
Plixorafenib (PLX8394) is an orally active inhibitor of the serine/threonine protein kinase B-Raf (BRAF) protein.Plixorafenib can selectively bind to and inhibit the activity of wild-type and mutant forms of BRAF, inhibiting the proliferation of tumor cells expressing mutant forms of BRAF.
Smiles
F[C@@H]1CCN(C1)S(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(cc23)-c2cnc(nc2)C2CC2)c1F
Molecular Formula
C25H21F3N6O3S
Molecular Weight
542.53
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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