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Swinholide A

Product Specifications

Target

Antifungal

Related Pathways

Microbiology/Virology

Bioactivity

Swinholide A is a polyketone compound that can be extracted from sponges and binds to actin to dimerize actin with Kd of about 50 nM. Swinholide A is a cytotoxin that stabilizes actin dimers and severs actin filaments. Swinholide A has antifungal activity and can damage the actin cytoskeleton of cells.

Smiles

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