Trypacidin
Product Specifications
CAS Number
1900-29-4
Target
Others|||Parasite
Related Pathways
Microbiology/Virology|||Others
Bioactivity
Trypacidin is a fungal metabolite originally isolated fromA. fumigatus.1It is active againstB. subtilisandM. bovis (MICs = 12.5 and 1.25 ?g/ml, respectively), as well asT. cruziandT. gondii (MICs = 5-10 and 10-20 ?g/ml, respectively) .1,2It reduces viability and induces lysis of A549 human lung cancer cells (IC50s = 7.4 ?M for both) .3Trypacidin increases survival in a mouse model ofT. gondiiinfection when administered in six doses of 12.5 mg/kg each.1
Smiles
COC(=O)C1=CC(=O)C=C(OC)[C@@]11Oc2cc(C)cc(OC)c2C1=O
Molecular Formula
C18H16O7
Molecular Weight
344.319
Shipping Conditions
Cool pack
Storage Temperature
-20°C
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