Furafylline

Furafylline is a potent and selective inhibitor of human cytochrome P450IA2 with an IC50 of 0.07 μM.

Product Specifications

CAS Number

[80288-49-9]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Cytochrome P450

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Furafylline.html

Purity

99.86

Solubility

DMSO : 12.5 mg/mL (ultrasonic)

Smiles

O=C1N(C2=C(N=C(C)N2)C(N1C)=O)CC3=CC=CO3

Molecular Formula

C12H12N4O3

Molecular Weight

260.25

Precautions

H302, H315, H319, H335

References & Citations

[1]Sesardic D, et al. Furafylline is a potent and selective inhibitor of cytochrome P450IA2 in man. Br J Clin Pharmacol. 1990 Jun;29 (6) :651-63.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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