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PW0787

PW0787 is a potent, selective, orally active, and brain-penetrant GPR52 agonist (EC50=135 nM) . PW0787 suppresses psychostimulant behavior[1].

Product Specifications

CAS Number

2624131-45-7

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

GPR52

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/pw0787.html

Concentration

10mM

Purity

98.79

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C(C1=CC=CC2=C1CCN2C3=NC=NC(CC4=CC(F)=CC(C(F)(F)F)=C4)=C3)NCCO

Molecular Formula

C23H20F4N4O2

Molecular Weight

460.42

Precautions

H315, H319, H335

References & Citations

[1]Wang P, et al. Discovery of Potent and Brain-Penetrant GPR52 Agonist that Suppresses Psychostimulant Behavior. J Med Chem. 2020;63 (22) :13951-13972.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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