Foslevcromakalim
Foslevcromakalim (QLS-101) is a ATP-sensitive potassium channel opener. Foslevcromakalim is the proagent used for ocular hypotensive effect[1][2].
Product Specifications
CAS Number
[1802655-72-6]
Product Name Alternative
QLS-101
UNSPSC
12352005
Target
Potassium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/foslevcromakalim.html
Purity
99.52
Solubility
DMSO : 60 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=P(O)(O)O[C@H]1[C@H](N2C(CCC2)=O)C3=CC(C#N)=CC=C3OC1(C)C
Molecular Formula
C16H19N2O6P
Molecular Weight
366.31
References & Citations
[1]Pervan-Steel CL, et al. Ocular Hypotensive Properties and Biochemical Profile of QLS-101, a Novel ATP-Sensitive Potassium (KATP) Channel Opening Prodrug. Invest Ophthalmol Vis Sci. 2022 Apr 1;63 (4) :26.|[2]WHO Drug Information-World Health Organization (WHO) .
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
Curated Selection
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